Global Certificate in Drug Delivery Pharmacokinetics
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⢠Drug Delivery Systems: An overview of various drug delivery systems, including oral, topical, pulmonary, and parenteral delivery. This unit will explore the advantages and disadvantages of each system and their impact on drug pharmacokinetics. ⢠Pharmacokinetics Basics: This unit will cover the fundamentals of pharmacokinetics, including absorption, distribution, metabolism, and excretion (ADME). ⢠Absorption and Bioavailability: This unit will focus on the factors influencing drug absorption, the importance of bioavailability, and various drug absorption models. ⢠Distribution and Protein Binding: This unit will delve into the principles of drug distribution, the impact of protein binding on drug disposition, and the concept of volume of distribution. ⢠Metabolism and Enzyme Kinetics: This unit will discuss the various metabolic pathways and enzymes involved in drug metabolism and the principles of enzyme kinetics. ⢠Excretion and Renal Clearance: This unit will cover the mechanisms of drug excretion and the role of renal clearance in the elimination of drugs. ⢠Pharmacokinetic Modeling and Simulation: This unit will explore the methods for pharmacokinetic modeling and simulation, such as compartmental and non-compartmental models, and their applications in drug development. ⢠Special Populations and Drug Interactions: This unit will discuss how age, gender, pregnancy, and disease can affect drug disposition and the potential impact of drug-drug interactions on pharmacokinetics. ⢠Clinical Pharmacokinetics: This unit will cover the application of pharmacokinetic principles in a clinical setting, including the importance of therapeutic drug monitoring and individualizing drug dosing regimens.
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